解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Herpes simplex virus (HSV) infection of the corneal stroma is the most prominent cause of scar formation impairing visual acuity and HSV keratitis is the leading cause of corneal opacity throughout the world. Suriname lacked test systems for microbial causes of ocular disease, therefore a polymerase chain reaction-bas...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23414
更新日期:2012-12-01 00:00:00
abstract::Rotavirus is a major cause of gastroenteritis in young children worldwide. There have been several recent reports concerning rotavirus isolation from adults, particularly in the elderly, presenting with gastroenteritis. In this study, the authors report on rotavirus outbreaks in five separate elderly care facilities b...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23416
更新日期:2012-12-01 00:00:00
abstract::Chikungunya fever a re-emerging infection with expanding geographical boundaries, can mimic symptoms of other infections like dengue, malaria which makes the definitive diagnosis of the infection important. The present study compares the utility of four laboratory diagnostic methods viz. IgM capture ELISA, an in house...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23406
更新日期:2012-11-01 00:00:00
abstract::Phylogenetic analysis was performed on hepatitis B virus (HBV) strains obtained from 86 hepatitis B surface antigen (HBsAg) positive donors from Thailand originating throughout the country. Based on the S gene, 87.5% of strains were of genotype C while 10.5% were of genotype B, with all genotype B strains obtained fro...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23363
更新日期:2012-10-01 00:00:00
abstract::Hepatitis C Virus (HCV) genotype 4 predominates in Middle East and Central Africa countries. Recently, it has become also prevalent in Southern European countries where it is thought to have been introduced through immigration and the movement of intravenous drug users. In Italy, the prevalence of genotype 4 is partic...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23384
更新日期:2012-10-01 00:00:00
abstract::Anal cancer is a rare disease. Nevertheless, it may be a reason for concern among groups in which its incidence is increasing: those who engage in anoreceptive intercourse, promiscuous persons, and those with sexually transmitted infections (HPV and HIV). The aim of this study was to evaluate the prevalence of abnorma...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23346
更新日期:2012-09-01 00:00:00
abstract::Epstein-Barr virus (EBV) serology continues to be the first diagnostic test when infectious mononucleosis is suspected. Due to possible mild immunosuppression in competitive athletes, EBV reactivation determined by increases in salivary viral load have been identified as one possible cause in recurrent respiratory inf...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23253
更新日期:2012-09-01 00:00:00
abstract::Saffold viruses (SAFV) have been discovered recently and they are classified into Theilovirus species in genus Cardiovirus in the Picornaviridae family. SAFV, especially those belonging to the genotype 2, have been difficult to propagate in laboratory cell lines. This study describes the successful isolation of an eff...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23352
更新日期:2012-09-01 00:00:00
abstract::Herpes zoster is a common infectious disease that can result in significant acute and chronic morbidity. The safety and efficacy of once-daily oral valomaciclovir (EPB-348) was evaluated for non-inferiority to 3-times daily valacyclovir, an approved therapy. In this study, 373 immunocompetent adults with onset of a he...
journal_title:Journal of medical virology
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/jmv.23329
更新日期:2012-08-01 00:00:00
abstract::Human parainfluenza virus 3 (HPIV-3) is a leading cause of respiratory disease in children worldwide. Previous sequence analyses of the entire virus genome, among different HPIV-3 strains, demonstrated that HN is the most variable gene. There is a dearth of data on HPIV-3 strains circulating in Saudi Arabia. In this r...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23326
更新日期:2012-08-01 00:00:00
abstract::BK polyomavirus (family Polyomaviridae) may cause hemorrhagic cystitis (BKV-HC) in hematopoietic stem cell transplant recipients. Eleven complete BKV genomes (GenBank accession numbers: JN192431-JN192441) were sequenced from urine samples of allogenic hematopoietic stem cell transplant recipients and compared to compl...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23240
更新日期:2012-07-01 00:00:00
abstract::Considering the limitations of cytology for detection of residual cervical cancer after radiotherapy, the aim of this study was to evaluate the frequency and viral load of high-risk HPV in cervical and vaginal samples during the early follow-up of patients treated for invasive cervical cancer and correlate the results...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23303
更新日期:2012-07-01 00:00:00
abstract::Although analytical treatment interruption is used as a strategy to test immunotherapeutic agents in HIV-infection, it may pose a risk for study participants. The potential risks of short-term interruption of antiretroviral therapy (ART) during treatment with an autologous dendritic cell immune-based therapy (AGS-004-...
journal_title:Journal of medical virology
pub_type: 杂志文章,随机对照试验
doi:10.1002/jmv.23297
更新日期:2012-06-01 00:00:00
abstract::Management of patients infected with high-risk HPV (hrHPV) despite normal colposcopy following abnormal cytology remains a clinical challenge. The aim of this study was to evaluate if, in that specific population, initial HPV 16 and HPV 18 viral loads are predictive of infection clearance over a 24-month follow-up. A ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23276
更新日期:2012-06-01 00:00:00
abstract::Epstein-Barr virus (EBV) genotypes can be distinguished based on gene sequence differences in EBV nuclear antigens 2, 3A, 3B, and 3C, and the BZLF1 promoter zone (Zp). EBV subtypes and BZLF1 Zp variants were examined in Japanese patients with infectious mononucleosis, chronic active EBV infection, and EBV-associated h...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23299
更新日期:2012-06-01 00:00:00
abstract::Molecular investigation was undertaken of circulating hepatitis A virus (HAV) associated with cases of acute diarrhea among children under 5 years of age in Kumba-Cameroon. Reverse transcription PCR, sequencing, and phylogenetic analysis of a 371 bp segment of the VP1/P2A junction of six isolates obtained from stool s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23266
更新日期:2012-05-01 00:00:00
abstract::During the period between 1998 and 2008, 48 representative measles viruses (MeVs) circulating in Thailand were subjected to genetic characterization. Three genotypes, G2, D5, and D9 were detected. The results suggested that measles genotype D5, which has been circulating since at least 1998, is the endemic genotype in...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23249
更新日期:2012-05-01 00:00:00
abstract::The Balkan Peninsula and Bulgaria in particular, is a well-known endemic region for Crimean-Congo hemorrhagic fever (CCHF). This study describes the prevalence of Crimean-Congo hemorrhagic fever virus (CCHFV) among tick populations from areas, previously recognized with emerging cases of CCHF disease in humans. These ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23214
更新日期:2012-04-01 00:00:00
abstract::Human parechoviruses (HPeVs) infection is associated with a wide range of clinical syndromes such as respiratory, gastrointestinal, neurologic diseases, and neonatal sepsis-like illness. The main objective of this study was to investigate the epidemiology of HPeVs infection in hospitalized patients in a period of 2 ye...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23197
更新日期:2012-04-01 00:00:00
abstract::Co-infection with hepatitis delta virus (HDV) and hepatitis B virus (HBV) has been shown to be associated with a more severe form of acute and chronic hepatitis. Cloning and expression of recombinant HDV antigen (rHDAg) in Escherichiacoli are described. Using purified rHDAg, a cost-effective indirect anti-HDV enzyme-l...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23212
更新日期:2012-03-01 00:00:00
abstract::Human metapneumovirus (hMPV) is a pathogen of the respiratory tract with a worldwide distribution. The purpose of this study was to identify hMPV as the cause of acute respiratory diseases in children admitted at Spedali Civili, a public hospital in Brescia, Italy. Eight hundred forty-six nasopharyngeal aspirate sampl...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23213
更新日期:2012-03-01 00:00:00
abstract::Although the rate at which mutations in the tyrosine-methionine-aspartate-aspartate (YMDD) motif of hepatitis B virus polymerase form is high during prolonged lamivudine (LAM) therapy, these mutations sometimes occur naturally in treatment-naïve patients with chronic hepatitis B. The prevalence of natural YMDD mutants...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23191
更新日期:2012-02-01 00:00:00
abstract::Noroviruses (NoV) and sapoviruses (SaV) are recognized as important causes of acute gastroenteritis in children worldwide. In this study, the prevalence and genetic variability of NoV and SaV were determined in hospitalized children <5 years of age with acute gastroenteritis in Hanoi, Vietnam. A total of 501 fecal spe...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23185
更新日期:2012-02-01 00:00:00
abstract::Previously, it was reported that productive viral infection, viral protein synthesis, and viral RNA replication of respiratory syncytial virus (RSV) operated efficiently in two human epithelial cell lines (HEp-2 and A549), but not in a human mast-cell line, HMC-1. Based on these observations, it was hypothesized that ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.23196
更新日期:2012-02-01 00:00:00
abstract::A combined hepatitis A and B vaccine is available since 1996. Two separate open-label primary studies evaluated the immunogenicity and safety of this hepatitis A and B vaccine (720 EI.U of HAV and 20 µg of HBsAg) in 306 healthy subjects aged 17-43 years who received three doses of the vaccine following a 0, 1, and 6 m...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22264
更新日期:2012-01-01 00:00:00
abstract::Persistent Epstein-Barr virus (EBV) infection is controlled tightly by virus-specific T cells. EBV infection is reactivated intermittently over time, even in apparently healthy carriers. Changes in frequency and reactivity of memory T cells, particularly of CD8(+) origin, have not been assessed in this context. It is ...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22258
更新日期:2012-01-01 00:00:00
abstract::A small percentage of renal patients become infected with the BK polyomavirus (BKV), a pathogenic virus that causes BKV-associated nephropathy (BKVN), after kidney transplantation. This study presents a simple, rapid, high-throughput method for BKV genotyping using high-resolution melt analysis (HRMA). Using this nove...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22239
更新日期:2011-12-01 00:00:00
abstract::During the period 2007-2008 several epizootics of Yellow fever with dead of monkeys occurred in southeastern Brasil, Paraguay, and northeastern Argentina. In 2008 after a Yellow fever outbreak an exhaustive prevention campaign took place in Argentina using 17D live attenuated Yellow fever vaccine. This vaccine is cons...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22236
更新日期:2011-12-01 00:00:00
abstract::Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) have similar transmission routes, implying that patients infected with HIV are at particular risk for HBV infection. Patients who are co-infected with HIV and HBV progress more rapidly to end-stage liver disease and different HBV genotypes may have a disti...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22174
更新日期:2011-11-01 00:00:00
abstract::Adenovirus infections are usually mild or even asymptomatic, but infections with the virus are being recognized increasingly as a major cause of mortality and morbidity in the immunocompromised, particularly hematological stem cell transplant patients where infections can be life threatening and mortality may reach 60...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22204
更新日期:2011-11-01 00:00:00
abstract::The general aim was to investigate the burden of respiratory virus illness in a hospital emergency department, during two different epidemic seasons. Consecutive patients attending an emergency department during two study periods (February/March 2009 and 2010) were enrolled using broad inclusion criteria (fever/preced...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22205
更新日期:2011-11-01 00:00:00
abstract::The ability to detect type-specific high risk HPV (HR-HPV) infections in samples from females and males is important for monitoring the epidemiology of HPV and the impact of vaccination. Type-specific detection concordance between paired urine and genital samples from females (n = 264) undergoing routine colposcopy an...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22167
更新日期:2011-10-01 00:00:00
abstract::Genotype-specific effects of parvovirus B19 (B19V) infections on left ventricular function in patients with dilated cardiomyopathy (DCM) have not been investigated so far. In this prospective clinical study, the prevalences of B19V genotypes in endomyocardial biopsies from patients presenting with inflammatory heart d...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22187
更新日期:2011-10-01 00:00:00
abstract::This study aimed to examine the application of hepatitis B surface antigen (HBsAg) confirmatory testing when diagnosing hepatitis B infection among young persons in Taiwan with a low prevalence rate of hepatitis B infection. HBsAg status, the presence of antibodies against HBsAg (anti-HBs), and the presence of antibod...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22127
更新日期:2011-09-01 00:00:00
abstract::Epstein-Barr virus (EBV)-associated post-transplant lymphoproliferative disease (PTLD) arises in up to 10% of organ transplant recipients and is fatal in ∼50% of cases. PTLD can be modeled in SCID mice using EBV+ve human B lymphoblastoid cell lines (BLCLs), and the current study investigated intraperitoneal (ip) inocu...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22164
更新日期:2011-09-01 00:00:00
abstract::Polyomavirus BK (BKV) is a common human polyomavirus that rarely causes clinical symptoms in immunocompetent individuals. However, BK virus reactivation occurs in 20-40% of kidney transplant patients and 1-10% of cases present with BK virus-associated nephropathy (BKVN) and reduced kidney allograft survival. In this s...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22106
更新日期:2011-08-01 00:00:00
abstract::Limited data are available describing human papillomavirus (HPV) genotype distribution among females with cytological abnormalities in Switzerland. Cervical cell specimens obtained from 5,318 women were screened routinely by liquid-based Pap smear. All specimens with cellular abnormalities were analyzed subsequently f...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22126
更新日期:2011-08-01 00:00:00
abstract::The contribution of viruses to lower respiratory tract disease in sub-Saharan Africa where human immunodeficiency virus may exacerbate respiratory infections is not well defined. No data exist on some of these viruses for Southern Africa. Comprehensive molecular screening may define the role of these viruses as single...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22120
更新日期:2011-08-01 00:00:00
abstract::The effect of antiviral treatment on apoptosis in chronic hepatitis B (CHB) has not been clarified. We evaluated the hepatic immunohistochemical expression of the pro-apoptotic bax and the antiapoptotic bcl-xL protein in HBeAg-negative CHB patients before and after treatment. In our study we included 72 paired biopsie...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.21780
更新日期:2011-07-01 00:00:00
abstract::WU and KI polyomaviruses (WUPyV, KIPyV) have been detected in respiratory, blood, stool, and lymphoid tissue, but not in urine samples. PCR based detection revealed higher frequency in immunocompromised individuals. In this study the prevalence of WUPyV and KIPyV was analyzed in respiratory, urine, and blood samples f...
journal_title:Journal of medical virology
pub_type: 杂志文章
doi:10.1002/jmv.22083
更新日期:2011-07-01 00:00:00